Vitamin D and Vitamin D binding protein: the inseparable duo in COVID-19
نویسندگان
چکیده
منابع مشابه
Letter: Covid-19, and vitamin D
Vitamin D is an immune modulator hormone with an anti-inflammatory effect. In this study the potential association between vitamin D and risk of Covid-19 disease were examined. Data of worldwide mortality rate of Covid-19 pandemic according to geographical distribution in 108 countries were analyzed. The results shows Covid-19 outbreaks and particularly mortality exhibit a decreasing North-Sout...
متن کاملVitamin D Binding Protein and Vitamin D Levels
1 Institute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China 2 Clinical Research, Diabetes and Endocrinology, Merck Research Laboratories, 126 East Lincoln Avenue, RY34B-148, Rahway, NJ 07065-0900, USA 3Department of Nutritional Science, Rutgers University, New Brunswick, NJ 08901, USA 4Division of Endocrinology, Metabolism an...
متن کاملVitamin D-binding protein prevents vitamin D deficiency and presents vitamin D for its renal activation.
Two mouse models in which the vitamin D-binding protein (DBP) or megalin, a DBP receptor, were knocked out have recently confirmed that DBP is essential for normal vitamin D homeostasis, and have revealed a major pathway for vitamin D activation (1, 2). DBP is also known as the group-specific component of serum (Gc-globulin). It is a highly polymorphic 58 kDa glycoprotein, which has been used a...
متن کاملCan Raising Vitamin D Status Slow Down Covid-19 Waves?
Several mitigation and suppression policies, such as social distancing, city lockdowns, remote working, testing, providing personal protective equipment and health care resource availability have been implemented by the governments in response to Covid-19 pandemic. Until now (October 23, 2020), over 1.14 million deaths in the world including 31,650 just in Iran have been officially attributed t...
متن کاملThe variation in free 25-hydroxy vitamin D and vitamin D-binding protein with season and vitamin D status
PURPOSE Serum 25-hydroxy vitamin D [25(OH)D] varies greatly with season at northern latitudes. The purpose of this study was to determine if the seasonal variations in serum total 25(OH)D are followed by a concomitant variation in free 25(OH)D or if the variation is damped by alterations in the binding capacity of DBP. METHODS Serum was collected from 540 healthy blood donors (60% men; mean a...
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ژورنال
عنوان ژورنال: Journal of Endocrinological Investigation
سال: 2021
ISSN: 1720-8386
DOI: 10.1007/s40618-021-01573-w